Diseases

Crohn's disease - symptoms, diagnosis and treatment

Crohn's disease is a very serious pathology, which is accompanied by intense abdominal pain, inadequate body nutrients, and frequent complications. The disease has a chronic course. Treatment of Crohn's disease with modern methods is unable to completely eliminate the pathological focus, but can maintain an adequate quality of human life, extending periods of remission and preventing the development of complications.

The main therapy of the disease is the use of medication, to which, as a supplement, various folk remedies are excellent. As auxiliary methods in the treatment of disease, the latest developments of scientists are used. However, in some cases, there is still the need for surgical intervention.

Drug therapy

Drug treatment of a disease consists of drugs of basic therapy, the purpose of which is made by a doctor, taking into account the severity of the pathology, as well as drugs to eliminate individual symptoms of both the disease and its complications. Also, therapy can be divided into relief and supportive: the first is designed to stop the process of destruction of the intestine, while the second is to maintain the absence of inflammation and prolong remission.

Basic therapy

It consists of one or more drugs, the purpose of which is to stop the autoimmune process in the intestine and reduce the level of inflammation in it.

A warning! Preparations for basic therapy are quite aggressive, have a range of side effects, so their appointment is made only by a gastroenterologist. Canceling medications or continuing a course of therapy is also a medical decision, since the patient himself assesses his own condition only from the point of view of the existing symptoms, whereas there are also objective criteria for evaluation.

How to treat Crohn's disease - with drugs such groups:

  1. Aminosalicylic acid preparations. They are the most important remedy for the treatment of the disease, possessing local antibacterial and anti-inflammatory effects, and suppress the activity of the autoimmune process. With these drugs begin treatment of the disease. They can be used in the form of tablets, as well as enemas and suppositories. The last two dosage forms are used in the defeat of the rectum and sigmoid colon to reduce systemic side effects.
  2. Glucocorticoids. These are synthetic analogues of hormones produced by each person's adrenal glands. They are very effective in reducing inflammation and blocking its autoimmune component, but have a significant amount of side effects. Before prescribing them, the physician must ensure that there is no bacterial infection in the human body.
  3. Cytostatics. These are drugs that inhibit the inflammatory activity in the intestine, but at the same time have a significant impact on cell division of the whole organism. Used in cases of severe Crohn's disease.
  4. Monoclonal antibodies are a relatively new group of drugs that are prescribed both to relieve exacerbation and to maintain remission of inflammation in the intestine.

Symptomatic therapy

  • anti-diarrheal medications,
  • dosage forms of calcium and vitamin D for the prevention of osteoporosis, especially if glucocorticoids are used in therapy,
  • if the intestine is affected so strongly that all food passes through it “in transit,” drugs of proteins, fats and carbohydrates can be prescribed for several days to feed a person through a vein,
  • hemostatic drugs,
  • antibiotics - with the development of purulent complications of the disease.

The latest treatment methods

Crohn's disease by American scientists is proposed to further treat:

  • linolenic acid in conjugated form - it reduces the level of inflammation,
  • stem cells, which are introduced during the main therapy: this restores the normal functioning of the immune system, and also accelerates the healing process in the intestine.

Healers recommend

A good addition to drug therapy is the treatment of Crohn's disease folk remedies. To do this, apply these recipes:

  1. Mix daisy flowers, sage leaves and centaury in equal shares, take 3 tbsp. spoon mixture, pour a glass of boiling water for 40 minutes, drain. Take 1 tbsp. spoon often - 7-8 times a day. The course is 12 weeks.
  2. 20 g of mustard seeds and aniseed fruit, 10 g of yarrow grass and buckthorn bark mixed with 30 g of licorice root, pour 200 ml of boiling water over this mixture, boil for 10 minutes, drain. Take 100 ml twice a day.
  3. In equal parts you need to mix the fruits of cumin, valerian roots, mint leaves and chamomile flowers, a tablespoon of the mixture is poured with a glass of boiled water, for an hour. This glass of infusion should be taken per day, divided into 3 introductions.
  4. For folk treatment of Crohn's disease, healers recommend using sage decoction. To do this, 100 g of dry raw material is placed in an enameled bowl, pour 3 cups of boiling water, boil for 10 minutes over low heat. Infuse - 20 minutes, strain, take 150-200 ml three times a day.
  5. Onion peel, which for this recipe needs a whole glass. Raw materials are placed in an enamel pan, pour 8 cups of water, bring to a boil. On a slow fire the pan with the lid half closed is an hour, while the new water is not added to it. Next, the broth is left to cool, filter. Drink 100 ml 3-6 times a day.

Such treatment of Crohn's disease by folk methods can significantly arrest the inflammatory process of the digestive tract and achieve stable remission while reducing the dosage of toxic drugs. However, this is true only if the patient adheres to the rules of dietary nutrition. Read more about them in the article: What should be the diet for Crohn's disease.

Surgery

Operations for Crohn's disease are performed according to strict indications, only if there are complications of the disease, such as:

  • intestinal obstruction
  • abscesses in the intestines,
  • perforation of the intestinal wall,
  • intra-abdominal bleeding,
  • fistulae
  • paraproctitis.


Such a cautious attitude to operations is connected with the fact that after them, in a year, in 70% of cases (later, more often), a relapse of the disease develops, repeated surgical intervention is often required. The recurrence rate is reduced by taking certain cytostatics and antibiotics,

Tip! Refusal of the operation for such complications as perforation, bleeding, fistulas or abscesses is not justified, since it leads to the death of the patient in a very short time. It is better to protect yourself from relapse with medication, but agree to the help of a surgeon.

Prognosis and disability

The prognosis for Crohn's disease is as follows. This disease is almost never cured. With its mild course of 90% of relapses, they respond well to treatment; in 10%, 1–3 times a year, exacerbations develop, which may be of varying severity. The factor that affects the risk of developing complications, even life-threatening ones, has not been clarified. It is believed that the 20-year survival rate for Crohn's disease is not different from that of other people.

Disability in Crohn's disease is a moot point. It is given if:

  • the disease, despite the treatment, is difficult,
  • there are complications
  • there is a disability,
  • difficult to choose therapy.

It is drawn up a year later, if within 4-5 months a person (with the availability of modern treatment) was forced to spend on a sick-list.

Symptoms of Crohn's Disease

Since this disease can affect any of the organs of the gastrointestinal tract, the signs will be completely different. Experts share the symptoms of Crohn's disease in:

  • are common,
  • local (depending on the location of the lesion),
  • extraintestinal disorders.

The first type of symptoms include fever, fever, malaise (signs of inflammation). If the temperature rises to very high rates (40 degrees), this indicates purulent complications of the disease. The decrease in body weight is due to the fact that the inflammatory organs of the gastrointestinal tract do not absorb all the necessary nutrients for the body.

Local symptoms of Crohn's disease include the following:

  • regular diarrhea, it is caused by the inability of the intestines to absorb nutrients, in severe cases, the processes of decay develop,
  • often recurring pain in the abdomen, it is similar to pain in appendicitis, occurs due to intestinal mucosa and constant irritation of the nerve endings,
  • infiltration (abnormal leakage of substances) and abscesses,
  • perforation of the intestinal walls,
  • intestinal obstruction
  • with the development of perforated fistula and ulcers in a patient there are bleeding.

Extraintestinal disorders are more associated with disorders of the immune system that affect the entire body. For example, the defeat of large joints (pain, limited mobility), inflammation of the sacroiliac area, visual impairment, skin rash.

Chronic form

In the picture of the symptoms of chronic form of Crohn's disease, the signs of intoxication come to the fore: weakness, malaise, fatigue, low-grade body temperature, loss of appetite and body weight, pain in large joints. Over time, regular diarrhea, bloating and abdominal pain, significant weight loss are added.

With the defeat of the large intestine increases stool, which may contain an admixture of blood. In some cases, in the right iliac region or in the central regions of the abdomen, a palpation of palpable palpable formation is palpated. The phalanges of the fingers take the form of drum sticks.

Usually, the chronic form of Crohn's disease occurs with exacerbations and prolonged remissions, causing severe consequences in the form of the appearance of anal fissures, ulcers, internal and external fistulas, massive intestinal bleeding, partial or complete obstruction of the intestine, sepsis. The resulting infiltrates can give complications, causing the development of cancer and subsequent disability. With a progressive course of the disease there is an unfavorable prognosis for the life of the patient.

Diagnostics

Before you figure out how to treat Crohn's disease, you must correctly diagnose. Therefore, to exclude other pathologies with similar symptoms, instrumental examination is appointed.

The following methods are commonly used:

  1. Colonoscopy. This study allows you to visualize the inner surface of the intestine.
  2. Irrigology. It provides an opportunity to see partial lesions of the intestine, narrowing of its lumen, relief of the intestine, ulceration or ulcers, thickening of the walls and a decrease in their activity.
  3. Ultrasound. It can be used to estimate the diameter of the intestinal loops, the presence of free fluid in the abdominal cavity.
  4. CT scan . This is done if Crohn's disease is complicated by diseases of other organs, and it is difficult to establish an accurate diagnosis. MRI allows you to study in more detail the condition of the intestine, the degree of its damage, the presence of fistulas, narrowing of the small or large intestine passage, and an increase in lymph nodes.
  5. Endoscopic examination. It is obligatory, with the help of it is carried out as a visual confirmation of the diagnosis, and take a piece of tissue for further examination under a microscope.

Be sure to use laboratory methods, including blood and feces to exclude infectious diseases of the intestine.

Crohn's disease treatment

With diagnosed Crohn's disease, the main treatment regimen is to use drug therapy aimed at localizing and reducing inflammation in the intestine, reducing the frequency and duration of exacerbations, as well as maintaining a state of sustained remission, that is, in anti-relapse treatment.

Severe cases may require the appointment of stronger drugs, complex treatment, and periods of exacerbations - surgery. The choice of treatment method depends on the severity of Crohn's disease, the dominant symptoms, the general health of the patient.

Complications

Crohn's disease may be accompanied by such complications as:

  1. Anemia.
  2. Intestinal bleeding.
  3. Perforation (violation of the integrity of the intestinal wall).
  4. Urolithiasis disease.
  5. Cholelithiasis.
  6. The occurrence of abscesses (ulcers) in the intestine.
  7. Development of intestinal obstruction (violation of the movement of intestinal contents through the intestines).
  8. The formation of fistulas (missing channels normally) and strictures (narrowing) of the intestine.

If a fistula develops inside the abdominal cavity, food that enters the intestine may bypass the sections responsible for the absorption of nutrients, as well as penetrate organs such as the bladder or vagina. The development of a fistula is a terrible complication, as there is a high risk of suppuration and abscess formation. Left without attention, this condition can be a threat to the life of the patient.

Prediction for life

Mortality in Crohn's disease is 2 times higher than in the healthy population. Most of the causes of death are associated with complications and surgery for them.

The disease has a relapsing course and in almost all patients at least one relapse occurs within 20 years. This requires constant dynamic monitoring of the patient to correct the therapy and identify complications of the disease.

The prognosis for life varies considerably and is determined individually. The course of Crohn's disease may be asymptomatic (with localization of the lesion only in the anus area of ​​the elderly) or to proceed in an extremely severe form.

What it is?

Crohn's disease is a chronic inflammatory process in the gastrointestinal tract that can affect all its parts, starting with the mouth and ending with the rectum. Inflammation develops simultaneously in the inner lining of the intestine and in its submucous layers, with a primary lesion of the terminal ileum.

Causes

Predisposing factors for the development of the disease are:

  • past viral infection (measles),
  • food allergies
  • stress and mental strain
  • smoking,
  • genetic predisposition.

To date, it has not been possible to identify the causative agent of Crohn's disease. However, the infectious theory is the basic version of the origin of the disease. This is due to the positive effect of treatment with antibacterial drugs. In addition, disorders of the immune system play an important role in the development of the disease. The autoimmune processes by which antibodies are produced against the own intestinal tissues and the insufficiency of the protective function of the immune system are an important link in the origin of the disease.

Prevention and prognosis for Crohn's disease

Ways of full recovery from this disease are not developed today due to the fact that the etiology and pathogenesis of the disease are not completely clear. However, regular adequate therapy of exacerbations and adherence to a diet and regimen, medical recommendations, and regular spa treatment contribute to reducing the frequency of exacerbations, reducing their severity and improving the quality of life.

The main, key points of prevention of exacerbations:

  • diet therapy, nutritional balance, the use of vitamin complexes, essential trace elements,
  • avoidance of stress, development of stress tolerance, regular rest, healthy life, normalization of biorhythms,
  • physical activity (mild exercise reduces the effects of stress, normalizes intestinal activity),
  • smoking cessation and alcohol abuse.

In 13-20% of patients there is a chronic course of the disease. With properly conducted treatment, the duration of periods of remission reaches several decades. As an independent disease, Crohn's disease is very rarely the cause of death of patients, and the percentage of mortality remains extremely low. Typically, patients receiving maintenance therapy, live to a ripe old age.

Risk factors

The risk factors for developing the disease include:

  • Age - the disease can develop at any age, but the frequency is much higher at a young age. In most patients, the diagnosis of Crohn's disease was confirmed before the age of 30,
  • Nationality - a higher risk of morbidity is observed among Europeans,
  • Tobacco smoking is the most important controlled risk factor for Crohn's disease. Bad habits not only increase the risk of disease, but also significantly aggravate its course. In smokers, there is an increase in the frequency of surgical interventions when planning treatment. If you smoke, quit
  • Non-steroidal anti-inflammatory drugs - uncontrolled intake and abrupt cancellation of these drugs (ibufen, diclofenac, etc., see pain injections) can lead to the development of inflammation in the intestine that worsens the course of Crohn's disease,
  • Oral contraceptives - if they are taken for a long time (over 5 years), the risk of this disease rises 3 times (see contraceptives - the pros and cons),
  • Environment - life in the city or in the industrial zone increases the risk of developing the disease. High risk is also observed among residents of northern areas in harsh and extreme climatic conditions,
  • Diet - high in fat and refined foods (with a reduced amount of nutrients) leads to gradual damage to the intestinal mucosa and the development of inflammation.
  • Food allergies - lactose deficiency, celiac disease (gluten intolerance), intolerance to any food.
  • Stress, mental overstrain - known to all factors of reduced immunity and, as a consequence, trigger mechanisms for the development of most diseases.

Aminosalicylates for oral administration (sulfasalazine, mesalamine)

These drugs are effective in the development of an inflammatory focus in the rectum. If the disease affects the small intestine, the drugs are useless. Previously, drugs of this group were widely used for the treatment of inflammatory diseases of the rectum, but at the moment a decision has been made to limit their use due to insufficient effectiveness and a large number of side effects.

Corticosteroids

Prednisiolone and other drugs in this group can reduce the inflammatory response of the body, regardless of the location of the primary focus. The disadvantages of their use are a large number of side effects, including edema, excessive growth of facial hair, insomnia, hyperactivity, as well as increased blood pressure, diabetes, osteoporosis, cataracts, glaucoma, and susceptibility to infectious diseases. These drugs do not work equally in different patients. Doctors resort to their help only if other methods of treatment had no result.

The new-generation corticosteroid Budesonide (Budenofalk) has a faster and more pronounced effect and has fewer side effects. However, its positive effect was recorded with the development of inflammation only in certain parts of the intestine. The duration of hormone therapy with corticosteroids should not exceed 3-4 months. Continuing treatment after achieving remission will not lead to further improvement and increase the risk of side effects. It is more expedient to switch to supportive therapy with immunosuppressants after achieving remission.

Immunosuppressants

Drugs in this group also relieve inflammation, but due to the effects on the immune system. In some cases, a combination of two immunosuppressants is used to achieve a more pronounced effect. Among the drugs used emit:

  • Azathioprine (Imuran) and Mercaptopurin (Purinethol). These are the most commonly used immunosuppressants in the treatment of inflammatory bowel disease. Side effects of short-term use include the suppression of bone marrow activity, the development of hepatitis and pancreatitis. Long-term use increases susceptibility to infections, and increases the risk of developing skin cancer and lymphoma,
  • Infliximab (Remicade), Adalimumab (Humira) and Tsertolizumab Pegol (Simzia). The mechanism of action of these drugs is to suppress the activity of plasma protein - tumor necrosis factor (TNF). The use of TNF inhibitors can effectively arrest the symptoms of Crohn's disease and achieve remission of the disease. This is one of the most promising areas for improving the treatment of this disease.

Preparations of this group are recommended to be used immediately after diagnosis, especially in case of suspected complicated course of the disease and the development of fistula.

Contraindications to the use of TNF inhibitors are tuberculosis, chronic viral hepatitis (B, C, etc.) and other serious infectious diseases.

  • Methotrexate (Rheumatrex). It is a drug used in the treatment of cancer, psoriasis and rheumatoid arthritis. But the appointment of his patients with Crohn's disease had a certain positive effect. It is usually used as an alternative remedy for the failure of other treatments.
  • Cyclosporine (Sandimmun Neoral, Panimun Bioral, Ecoral) and Tacrolimus (AstagrafXL, Advagraf, Prograf, Takrosel). Usually used for Crohn's disease, complicated by the development of fistulas, these drugs can also be used for uncomplicated disease in the absence of improvement from the standard therapy. The use of cyclosporine is associated with some severe side effects (kidney and liver damage, seizures, infectious diseases). Long-term use is contraindicated
  • Natalizumab (Tizabri) and Vedolizumab (Entivivo). The mechanism of action is to prevent the binding of integrins (cellular molecules of leukocytes) with surface molecules on the intestinal mucosa. The rupture of communication prevents the development of autoimmune inflammation, thereby removing the symptoms of the disease. Natalizumab is recommended for use in patients with moderate or severe disease that does not respond to treatment with other drugs.

The use of the drug is associated with a certain risk of multi-leucoencephalopathy - a brain disease that can lead to death or disability. Therefore, before starting treatment, the patient must become a member of a special program with a limited distribution of the drug.

Vedolizumab also passed clinical trials and received approval for use in Crohn's disease. The mechanism of action of the drug is identical to that described above, but the advantage is that there is no risk of developing leukoencephalopathy,

  • Ustekinumab (Stelara). This medicine has been used to treat psoriasis. Thanks to the studies, the effectiveness of the drug in relation to Crohn's disease was noted.

Antibiotics

Antibiotics are prescribed for the development of fistulas or abscesses to combat infectious complications. Some researchers also suggest that antibiotics can reduce the degree of adverse effects of opportunistic bacteria on the damaged intestinal wall. However, the proven efficacy of antibiotic therapy in relation to the outcome of Crohn's disease has not yet been identified.

The most commonly prescribed antibacterial drugs for Crohn's disease include:

  • Metronidazole (Flagyl, Trihopol, Klion). Once metronidazole was the most common antibiotic in the treatment of this disease. Although its use is associated with the risk of side effects such as weakness and pain in the muscles, numbness and tingling in the hands and feet,
  • Ciprofloxacin. This drug, the use of which in some patients reduces the severity of symptoms of Crohn's disease. It is currently preferred over metronidazole.

Other medicines

In addition to combating inflammation, other drugs can be used to improve the condition. Depending on the severity of the disease, doctors may recommend:

  • Antidiarrheal drugs - methylcellulose (Citrusel) is suitable for an easy course. In more severe cases, Loperamide (Imodium) is recommended. To begin treatment with these drugs can only be recommended by the attending physician,
  • Analgesics - Acetaminophen (Tylenol) can relieve moderate pain. Note that in this case, common analgesics are contraindicated (Ibuprofen, Naproxen). Their use may worsen the course of the disease and lead to the development of more pronounced symptoms,
  • Iron preparations for anemia - for chronic intestinal bleeding, iron deficiency anemia may develop, for the treatment of which these drugs are prescribed,
  • Vitamin B12 Injection - Crohn's disease can lead to the development of B-12 deficiency anemia. To prevent its further progression, vitamin preparations are prescribed,
  • Calcium and vitamin D - the disease itself and the hormones used to treat it increase the risk of osteoporosis. The described drugs are prescribed to prevent this complication.

If diet, lifestyle changes, drug therapy, and other methods have been ineffective, surgical treatment is recommended for the patient. About half of all patients with Crohn's disease in the course of treatment suffer at least one surgical procedure. However, it does not provide a cure for the disease.

Surgical treatment consists in removing the damaged part of the intestine with the subsequent imposition of the anastomosis between healthy areas. Surgical intervention is also necessary for the treatment of fistulas and drainage of abscesses, as well as the development of intestinal obstruction.

The positive effect of surgical treatment for Crohn's disease is usually temporary. The disease often recurs, causing inflammation in the vicinity of the previous focus. The best tactic is to continue supportive drug therapy after surgery.

There is no reasonable evidence that certain foods cause Crohn's disease. But avoiding the use of certain types of food can significantly reduce the severity of symptoms of the disease.

Many doctors recommend patients to keep a diary to control their diet. If, after consuming any product, the patient notes a worsening of the condition, in the future he will be able to avoid aggravation simply by adjusting the diet.

Recommendations regarding nutrition:

  • Limit the use of flour and baking,
  • Give preference to low-fat foods,
  • Give up eating spicy foods, alcohol,
  • Eat small meals 5-6 times a day
  • Drink enough liquid
  • Take multivitamin complexes.

Examples of Celebrities with Crohn's Disease

Only in the United States there are about 700 thousand patients with Crohn's disease. Although the symptoms of the disease can significantly impair the patient's quality of life, a properly selected treatment plan allows patients to remain on their feet. For example, many famous athletes were able to challenge this serious disease and, despite everything, reach the peak of their careers. Below are their stories about how they managed to cope with their condition and achieve superiority on the playing field.

David Garrard: American Football. Defender

About 30 centimeters of bowel removed due to Crohn's disease. The fight against the disease for David, a 35-year-old former player of the Jacksonville Jaguars team, started back in 2004, when he was tormented by intolerable stomach pains after eating. In 2005, in an interview for TheNewYorkTimes He stated that, in his opinion, he had caught an intestinal infection and was in no hurry to consult a doctor for three months. Garrard began to lose weight heavily, which is not very good for a football player, until supportive therapy and surgery did not return everything to its place. Despite his age and Crohn's disease, David continues to perform on a lined field: for 2013-2014, he signed a contract with the New York Jet team.

Cynthia McFadden

The correspondent of the channel ABC News, McFadden for the first time felt the excruciating pain caused by Crohn's disease, which her friends figuratively dubbed "George", in their 2 years of college. “They did not ask how many bouts of diarrhea I had during the day. Instead, they said, “How is George doing?”, Says Cynthia in an interview with People magazine in 1994.

After she developed internal bleeding in 1979, she was removed 4.5 meters of the intestine. Since then, McFadden has experienced a stable remission, and she continues to work at the American Foundation for the Control of Crohn's Disease and Colitis.

Kerry Johnson: Participant in the Kayak Olympics

Kerry Johnson has performed in three Summer Olympics despite the diagnosis of Crohn's disease. In 2003, anemia, weight loss and exhaustion forced her to stop training. After many tests, she was diagnosed with Crohn's disease, but with medical help she was able to cope with the disease. A year later, she qualified for her first Olympic Games in Athens. At the recent London Games in 2012, Johnson reached the semi-finals in two categories. Now, after leaving the sport, Kerry has directed efforts to support people with Crohn's disease, urging others not to be afraid of their condition.

Frank Fritz

Fritz, one of the stars of reality shows AmericanPickers on the History Channel, an antique treasure hunter who fought Crohn's disease for nearly a quarter of a century.

“Crohn's disease is like a duck,” he tells a Crohn's Advocate magazine reporter, “Ducks seem to be calm, quietly swimming on the water surface, but under the water they hit the flippers like crazy. Similarly, for people with Crohn's disease, nothing is visible from the outside, but I have to make great efforts to control my condition. ”

George "The Beast" Steele - a fight without rules

His real name is Jim Myers, but wrestling fans know this athlete as George “The Animal” Steele from World Wrestling Entertainment. Crohn's disease was diagnosed in Steele in 1988. At that time, doctors said that the lesion of the rectum was progressing so quickly that it needed to be removed, but he refused. After many years of medical treatment, which led to the development of a number of associated diseases, doctors still had to remove his rectum in 2002. Steele says he finally regained his former health, and now travels around the United States as a motivational speaker.

Mike McCredy

Rocker McCready, guitarist, head of the Pearl Jam group, considers himself lucky, despite Crohn's disease. In 2007, in an interview for BigButtRadio.com, he said that he was happy that he could do what he really loved. “I tried to show people that despite the illness, we still have life and career.”

James Morrison - Golf

British golfer James Morrison found out that he has Crohn's disease more than 10 years ago. During the 2011 French Open Championship, an attack caused him to go to the hospital, but Morrison braced himself and finished the tournament.The cause of the disease has not been clarified.

Kevin Dinin. Hockey.

Former professional hockey player Kevin Dinin survived hard times, joining the fight against Crohn's disease. “It was a really instructive lesson, because a quick decision is not an appropriate word for this state,” Dinin said in an interview for the magazine. USAHockeyMagazine in 2010. "This is a chronic, debilitating disease that lasts throughout your life." Like many other professional athletes, Crohn's disease arose in the path of a hockey player's only promising career. But he managed to take the disease under control and continued to play in the NHL for another 16 years. Dinin is currently coaching the NHL Florida Panthers team.

Matt Light - Football

Former New England Patriots midfielder Matt Light learned about his diagnosis in 2001, during his debut season, after which for 10 years he waged a quiet fight with his illness. Throughout his football career, Light could not take most of the prescribed drugs and missed the game due to exacerbations of symptoms. Three times the champion of the Super Bowl underwent an operation in which more than 30 cm of its intestines were removed. The retired athlete now shares his story with others to increase literacy and self-confidence to combat Crohn's disease.

Dwight D. Eisenhower

34 President of the United States was diagnosed with Crohn's disease in 1956. Due to the severity of the condition, he was soon operated on. Commanded by Allied forces in Europe during the Second World War, Eisenhower managed to win a repeat election despite heart problems and severe intestinal inflammation.

The prognosis of the disease varies considerably and is determined individually. The course of Crohn's disease may be asymptomatic (with localization of the lesion only in the anus area of ​​the elderly) or to proceed in an extremely severe form.

In 13-20% of patients there is a chronic course of the disease. With properly conducted treatment, the duration of periods of remission reaches several decades. As an independent disease, Crohn's disease is very rarely the cause of death of patients, and the percentage of mortality remains extremely low. Typically, patients receiving maintenance therapy, live to a ripe old age.

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