Indications and contraindications to the use of the drug
Panzinorm is recommended for use in the presence of a number of such symptomatic manifestations and diseases:
It was noted that in the case of the chronic form of pancreatitis, Panzinorm can not only stimulate the pancreas, but also significantly reduce pain.
With regard to contraindications to the use of drugs, they are:
If we compare Creon and Panzinorm, the presence of contraindications for these drugs is identical.
Instructions for use and side effects
If the patient is unable to completely swallow the capsule for any reason, then it should be opened and the powder present inside can be combined with food that you do not need to chew on when you eat (for example, yogurt, fruit puree or potatoes).
During the use of the drug is very important to use a lot of liquid, because in the opposite situation there may be such an unpleasant problem as constipation.
The dosage of the drug is determined by the doctor, taking into account the type of illness and the severity of its course.
On average, one dose of a drug for an adult ranges from ten to twenty-five thousand IU of lipase.
If the patient’s above dosages are not followed, the following side effects may develop:
Features of the application of Creon
Indications and contraindications to the use of the drug
A drug like CREON is prescribed for use in the following situations:
With regard to contraindications to the use of the drug, there is almost no difference compared with taking Panzinorm.
Among the contraindications to the use of the drug, there are the following:
- the course of exacerbation of chronic pancreatitis,
- excessive sensitivity to pork,
- acute pancreatitis.
Dosage and adverse effects
In case of non-compliance with these dosages, the following side effects may develop:
- abdominal pain,
- nausea and gagging,
- rash on the skin,
- anaphylactic shock,
- changes in stool condition,
In addition, there may be side effects in the form of severe itching of the skin.
The difference between Creon and Panzinorm
In order to understand which of the presented drugs is better, you first need to figure out how they differ.
Among the main differences between the drugs are the following:
But despite these differences of drugs, after a recent study, it was determined that these funds are absolute analogues of both composition and price.
It should be noted that the presented drugs are quite often compared with such a drug as Mezim. These 3 drugs are almost identical, the difference lies only in the number of constituent elements.
You should also go for a consultation with a doctor if refusal to take medications is necessary, because if after a long use of these medicines it is abruptly abandoned, then "withdrawal syndrome" is possible. As a result of this syndrome, the body is unable to independently produce the enzymes necessary for the normal functioning of the gastrointestinal tract.
As already noted, the cost of medicines is almost identical, only Mezim costs a little less, which is practically no different from the presented drugs.
About pancreatic diseases
All this leads to violations in the gastrointestinal tract, and they, in turn, cause a reduced level of enzymes that break down food into less complex components for good absorption by the body. And this directly affects the pancreas, diseases of which are characterized by the irreversibility of the processes in its tissues.
Pharmacological characteristics of Pancreatin
Pancreatin is recommended for use by people who suffer from chronic pancreatitis, enzyme deficiency, gastritis, flatulence and any violations in the digestive process.
People often ask if Mezim, Festal or Pancreatin are better.
At the same time, the drug is contraindicated in patients in whom its animal component causes intolerance. Plus, it should not be used by pregnant women and pancreatitis sufferers in the acute stage.
What is better Mezim or Pancreatin? Reviews on this subject abound.
Since the concentration of pancreatin in this medicinal product is low compared to other analogues, they treat only mild levels of gastrointestinal disorders. The doctor can prescribe at one time from 1 to five tablets - it depends on the patient's body weight.
So, which is better - Mezim or Pancreatin?
Pharmacological characteristics of Mezima
A sufficient amount of the main active ingredient makes this drug more effective than Pancreatin in combating the symptoms and causes of housing and public utilities ailments. But at the same time it is worth being careful with its dosage.
The drug itself is made in Germany, so its price is significantly higher than that of Pancreatin, and therefore the risk of running into a fake is also higher.
Which is better - Panzinorm, Mezim, Festal, Creon, Pancreatin? All these tools are very similar in their action.
Festal is a combined enzyme preparation that helps to improve the processes of digestion. The main pharmaceutical property of this drug is to ensure the processes of cleavage of proteins, fats and carbohydrates in the small intestine.
We give only a partial list of Festal analogues, including drugs that are the most popular and often prescribed today:
Which is better: Mezim or Pancreatin or Creon, it can be very difficult to decide.
Side effects of this medication can manifest as diarrhea, nausea, vomiting, and increased urea levels.
This drug is effective in the treatment of both light and serious forms of gastrointestinal disorders, as the content of the active substance in it is increased.
So, the advantages of Mezim include clear and detailed information about the doses of all the substances in one tablet, the increased effectiveness of the effects on the patient's body, as well as the proven German quality. And its disadvantages are the high cost, a higher number of side-effects in comparison with Pancreatinum, plus the probability to purchase a fake instead of the original medicine.
And in the opinion of people, which is better - Mezim or Pancreatin. About this below.
What say reviews
We studied the reviews that people left on the sites where these drugs are sold and on the forums. Disputes about the benefits of one of these two drugs are very common, but the main conclusions are:
What is better: Mikrasim, Mezim, Pancreatin, you decide.
Analysis of the pros and cons of both drugs does not give an unequivocal answer to the question - which of them is still better? Be that as it may, their appointment should be prescribed by a doctor, namely a gastroenterologist. He must answer your questions and justify the choice of this medicine. However, we can say that the dosage of the active component of Mezim and Pancreatin is very individual, depends on many conditions - on the nature of the disease, the degree of its severity, the presence of contraindications, the patient's body weight, etc. In any case, you should not prescribe yourself these medicines yourself. At best, there is a chance to experience their side effects. Well, in the worst - to be in the hospital.
What is better Mezim or Pancreatin, it is better to check with the doctor.
Features of Panzinorm intake
The drug "Panzinorm" - a well-known drug, the main active substance of which is Pancreatin. It is characterized by strong lipase activity, this is important, since the production of this enzyme is most often disturbed.
A remedy called Panzinorm is recommended to take in the following diseases and conditions:
- insufficient secretion of enzymes in the pancreas due to genetic or congenital causes,
- obstruction of junction passages (stone, parasites),
- the patient has cystic fibrosis,
- chronic pancreatitis,
- state of the operation field - gastrectomy or pancreatectomy,
- tumor type pancreatic tumors,
- digestive disorders after radiation therapy.
It is important to note that in certain diseases of the digestive organs, Panzinorm can help eliminate pain and discomfort in the abdomen.
To take the drug "Panzinorm", the main substance of which is Pancreatin, is prohibited without a doctor's prescription, as this can increase the symptoms of the disease, as well as lead to serious complications.
Like the other medication, Panzinorm has a number of contraindications for which it is strictly prohibited to treat with this remedy.
- allergic reaction to pork (the main active ingredient of the drug is created on the basis of an extract from the pancreas of this animal),
- the presence of hypersensitivity to one or several components of the drug, and this includes not only the main substance, but also additional components,
- inflammation in the pancreas, which is acute;
- pregnancy (relative contraindication - the minimum dosage of preparations containing digestive enzymes is possible during gestation of the fetus).
If we compare Kreon and Panzinorm with each other, the contraindications for these drugs are identical, therefore, when choosing a medicine to treat the organs of the gastrointestinal tract, it is required to pay attention not only to contraindications, but also other characteristics of the drugs.
Instructions for use Panzinorm and its side properties
If a person has problems with the work of the digestive system, Panzinorm should be drunk before or during meals. To take this medication, like Kreon, it is required in the same way: we take a capsule and, without getting any more, we swallow. After that, it is imperative that you take the pill with water, otherwise it may cause serious damage to the lining of the stomach or esophagus.
If the patient is unable to swallow the capsule for a number of reasons, it must be carefully opened and the powder mixed with food that is not needed to be chewed. For example, it could be:
- mashed potatoes,
- grated fruit
When taking the medicine, the patient should drink plenty of fluids - if this is not done, the victim may develop constipation due to a lack of water, which will significantly impair the functioning of the digestive tract.
It is important to note that the dosage of the drug "Panzinorm" is prescribed by the doctor individually, it depends on the diagnosis, the severity of the disease and dietary habits. Even if the patient reads in the instructions how to take the medicine correctly, it is not worth starting the treatment yourself, otherwise it can lead to unpleasant consequences.
On average, the dosage of therapeutic agent for an adult with problems with the work of the digestive tract is 10-25 thousand units of lipase. If the patient takes the medicine correctly, it will help to normalize the activity of the digestive organs.
If you take Panzinorm requires a child whose age is less than 4 years old, a single dose of the drug should be carried out in the dose that will be calculated by the doctor. This is done as follows - 1 thousand UNITS per kilogram of weight.
If the patient does not follow the rules of taking the drug or exceeds the dosage, he may have the following side effects:
- The appearance of lesions on the body, redness of the skin, the addition of itching, as well as causeless tearing. In a severe case, anaphylactic shock or bronchospasm may develop. If the patient does not take measures in time, the state of health will greatly deteriorate.
- Dyspeptic disorders - nausea, retching, abnormal stool (diarrhea), as well as irritation in the anus. These side effects are less dangerous in comparison with previous ones, but it is desirable to eliminate them soon after development. If this does not happen, the medication is required to stop completely.
Judging by the reviews, the correct use of the drug helps to restore and improve digestion. However, to achieve this, it is imperative to observe the dosage and follow the recommendations of the doctor.
Description of the drug "CREON"
Creon is a drug endowed with a powerful enzyme action that is required to be taken in case of diseases of the digestive organs.
Proper medication allows the body to absorb proteins, carbohydrates and fats entering the digestive tract with different foods. The drug relieves the stomach, if he got a lot of fatty or heavy food.
Doctors Creon is prescribed for the treatment of the following diseases:
- cholestatic hepatitis,
- chronic pancreatitis,
- obstruction of ducts, which is caused by the development of a malignant tumor, stones or accumulation of parasites,
- recovery of the body after the patient undergo surgery - cholecystectomy, pancreathectomy,
- cystic fibrosis,
- intestinal inflammation
- condition after resection of the stomach, which may be partial or complete.
Contraindications, as mentioned earlier, in Creon are the same as in Panzinorm. Therefore, comparing medicines is required according to other selection criteria.
Contraindications for the use of drugs include:
- pancreatitis, which is acute or chronic in the acute stage,
- increased sensitivity of the body to pork protein,
- intolerance to the components in the composition of the tool.
Before taking the medicine, it is imperative to visit the doctor who will conduct the examination and also prescribe the correct treatment to the patient.
How to take the medicine, and what are its side effects
If you decide that it is better to take Creon, then it should be noted that the dosage is the same for both drugs. Therefore, there is no difference in them. The average dosage of the drug is fully consistent with the drug "Panzinorm". Adults need to take 10-25 thousand units of the drug, and for children under the age of 4 years the medication is calculated based on the patient's weight - 1000 units per kilogram of body weight. Patients over 4 years old are prescribed 500 U per kilogram of weight.
In order for the medicine to work well, it should be taken correctly and in no case should the dosage be disturbed, especially if the treatment is given to the child.
If the patient violates the recommendations of the doctor, he may experience side effects, because of which the medication must be stopped. Side effects include:
- constipation, not passing a long time,
- development of anaphylactic shock,
- rash on body and face
- nausea that can turn into vomiting,
- pain or discomfort in the abdomen.
Also to the additional side effects is the appearance of itching on the skin, which occurs due to a strong overdosing of the drug.
Sometimes doctors do not prohibit patients from taking Creon if they have minor side effects - the main thing is to monitor their well-being and in case of severe deterioration consult a doctor in time.
What is the difference between drugs?
To find out which particular medicine from the two presented above is better, it is necessary to figure out what remedies differ among themselves if they have many similar characteristics.The main differences between medications are:
- CREON contains more pancreatin (the main active substance) than Panzinorm. In addition, it correctly calculated the ratio of some components, for example, starch. Based on this, you can see that the composition of Creon is better and more effective.
- The composition of the two therapeutic agents are additional substances. A pharmaceutical manufacturing company must indicate the quantity of auxiliary components. This makes it possible to understand whether they can have a harmful effect on health in people who are prone to developing allergies or are hypersensitive.
- Creon due to microspheres in the capsule begins to act only after penetration into the small intestine. Panzinorm, on the contrary, is absorbed in the stomach immediately after taking the drug. Part of it may break down if the patient has a high level of acidity.
Based on the above information, we can conclude that the reception of Creon is considered more effective in cases where diseases of the digestive organs occur in severe form. The use of Panzinorm is best done when high doses are not required. This medicine can not help with some serious diseases of the digestive system.
Recent studies have shown that both drugs are considered analogues of each other in composition, indications, contraindications and price. The only difference is in manufacturing technology. When a doctor prescribes one medicine, it is not worth replacing it with another one at your own discretion.
Basic indications for use
A specialist gastroenterologist may prescribe a drug for the following diseases:
- Lack of digestive enzymes in the patient's pancreas,
- Cystic fibrosis
- Chronic pancreatitis in adults
- Malignant growths in the pancreas,
- The recovery period after surgery in the digestive tract,
- Obstruction of the pancreatic or bile ducts,
- Shwachman-Diamond Syndrome,
- Acute pancreatitis (since the end of the period of full starvation),
- Moreover, it has been proven that Panzinorm not only has a stimulating effect on the pancreas in chronic pancreatitis, but also significantly reduces pain. What can not be said about the drug with a similar composition - "CREON".
All of the above indications for use of Panzinorm are identical with the indications for treatment with Creon. What of them is better, let's try to figure it out.
How to take "Panzinorm"
For a patient with digestive disorders, it would be better if Panzinorm was taken before or during meals. The capsule of the drug, as well as “Creon”, is swallowed whole, squeezed with a sufficient amount of liquid, since the granules of the drug can significantly damage the oral mucosa.
If the patient is not able to swallow the capsule completely, it is necessary to open it and mix the contents with any food that does not require chewing (yogurt, fruit or mashed potatoes).
It is worth remembering that a lack of fluid in the patient's body during the period of treatment with Panzinorm or Kreon can provoke prolonged constipation.
The dose of the drug is selected by the attending physician depending on the degree and severity of the disease.
However, in any case, the initial dose of Panzinorm should be 10,000–25,000 U of lipase during each main meal.
For children under 4 years of age, the initial dose of the drug will be 1000 IU of lipase per 1 kg of body weight during each meal. For young patients 4 years and older, the dosage should be 500 IU of lipase per 1 kg of body weight during each meal.
It should be remembered that for each patient, individual choice of dosage is preferable, depending on the nature of the disease and its severity.
Contraindications to receive "Panzinorm"
The preparation of the enzyme group Panzinorm, as well as Creon, has the following contraindications:
- Individual intolerance to any of the components of the drug,
- Hypersensitivity or intolerance to pork,
- The period of acute inflammation of the pancreas,
- Pregnancy (in the period of gestation of the infant, it is best to consult with your doctor about taking the preparations of the fermentation group).
Side effects from the reception "Panzinorm"
As in the case of the uncontrolled drug “Kreon”, the drug “Panzinorm” can cause the following side effects:
- Immune system (various types of rash, itching, redness of the skin, increased tearing, bronchospasm, anaphylactic reaction, obstruction of the upper respiratory tract),
- The digestive system (nausea, dizziness, vomiting, abnormal stool, irritation and itching in the anus).
In case of detection of these side effects, you must urgently stop taking the drug and contact your doctor. The specialist will replace the drug with a more suitable one for you and will carry out a restorative cleansing therapy.
And yet: "Creon" or "Panzinorm"?
Having dealt with the composition of the new drug "Panzinorm" and familiarized with its action, we come to the conclusion that both drugs - and "Creon" and "Panzinorm" are absolute analogues.
The difference in preparations consists only in the price and in the name of the manufacturer.
Thus, the drug "Creon" is a product of the German company "Abbott Products GmbH". While “Panzinorm” is produced in Slovenia under the KRKA brand. Both drugs are recognized by physicians around the world as effective in treating enzyme deficiency.
Deciding for yourself what is better to take - “Creon” or “Panzinorm”, do not forget to consult your doctor!
Important! Self-treatment can lead to extremely negative consequences. And therefore, do not postpone the visit to the doctor indefinitely if you find yourself in the unpleasant symptoms of diseases of the digestive system. It is better to nip the disease in the embryo than later undergo a long recovery course.
Indications for use
Both drugs have the same indications for use. First of all, Creon or Panzinorm is prescribed for the following diseases:
- chronic pancreatitis in the acute phase,
- pancreas cancer,
- reduced enzyme function in the elderly,
- cystic fibrosis
In addition, the drugs are well help to alleviate the symptoms of dysfunction of the digestive system.
It happens with biliary obstruction, cholestatic hepatitis, cirrhosis of the liver. For children, Kreon and Panzinorm are suitable for treating the effects of severe diarrhea and the active growth of bacterial colonies in the small intestine. Also, these drugs are prescribed for partial removal of the stomach, total gastrectomy and gastrostasis.
Both medications help remove symptoms associated with dietary errors, heavy meals, and poor chewing of food.
Therapy is prescribed by the attending physician, who will be able to objectively assess the patient's condition and the presence of contraindications to enzymatic means. When choosing a drug, it must take into account all the individual characteristics of the body.
Composition of drugs
Panzinorm and Creon contain the same enzymes. The only difference is in the quantitative part. They contain lipase, amylase and protease.
Each of them contributes to the assimilation of the necessary substances:
- lipase - breaks down fats, as well as vitamins A, D and E,
- amylase - absorbs carbohydrates
- protease - is responsible for the breakdown of proteins.
The main active ingredient in both drugs is pancreatin, which includes all the listed enzymes. Creon has a dosage of 10,000, 25,000, 40,000, while Panzinorm is available in only two versions - 10,000 and 20,000. Preparations are easily interchanged, you can take one that is convenient to dose based on the daily dose of the necessary enzymes.
Mechanism of action
The capsule shell dissolves quickly in the duodenum. Only then all the necessary enzymes are released from it and help to digest food. As a result, the mechanism of human exposure is simple - the main substances enter the intestine, break down proteins, fats and carbohydrates, respectively, the latter are easier absorbed through the intestinal walls into the blood.
Due to this effect, a healthy person can take these medicines if they need to cope with the weight of fatty, fried or unhealthy food. Also, drugs can cope with symptoms such as nausea, weakness, which appeared on the background of overeating. Drugs do not change the work of the digestive tract, but simply add active enzymes. This contributes to the rapid digestion of food and the normalization of the bowels. In addition, the load is removed from the pancreas.
Which drug to choose
Creon and Panzinorm are generics. Their main differences are the country of origin, as well as the cost of drugs in the pharmacy chain.
Creon is produced in Germany, contains 150 mg of pancreatin and excipients, the amount of which is calculated by a special formula. Available in enteric capsules with different amounts of the main substance. The cost of the drug at the pharmacy depends on the dosage:
- Creon 10 000, 20 capsules - 276 rubles,
- Creon 25 000, 20 capsules - 539 rubles,
- Creon 40 000, 50 capsules - 1458 rubles,
- Panzinorm 10 000, 21 - 130 rubles,
- Panzinorm 10 000, 84— 400 rubles,
- Panzinorm 20 000, 10 - 100 rubles.
Panzinorm is manufactured by KRKA. The drug is available in the form of tablets and capsules. The cost of Creon is less, and therefore it is more often prescribed. With the same methods of effects on the body, at the price of medication Panzinorm clearly wins.
Drugs are popular among the population because they are well tolerated and have a minimum of contraindications. But consultation with a doctor in any case is necessary, because an excess of enzymes, with their uselessness, can harm the body, especially for children.
In most cases, the use of expensive Creon is justified in case of complicated course of gastrointestinal diseases, as well as in infancy. The drug is allowed to give children from birth. Panzinorm has contraindications for use in patients up to 3 years, as well as in patients with cystic fibrosis up to 15 years.
If you just need to adjust your digestion after a feast or unsuccessful diet, it is enough to buy Panzinorm and take it in the required dosage.
The purpose of the drug "Panzinorm"
The instructions for use of these tablets give clear instructions on what conditions should be given such therapy. Experts identify two main reasons:
- Insufficiency of pancreatic secretory function.
- Disturbance of food digestion.
Similar conditions are explained by a number of pathologies:
- cystic fibrosis
- Remheld syndrome,
- intestinal infections
- chronic liver and bile duct diseases,
- conditions after resection of the small intestine and stomach.
The composition and action of enzyme drugs
Drugs like Festal, Creon, Panzinorm, Pancreatin and Mezim are complex enzyme preparations. The peculiarity of the panzinorm dragee lies in the fact that the main ingredients have special shells:
- under the first, soluble layer are amino acids and an extract of the gastric mucosa, which stimulate the production of its own secret,
- under the second acid-resistant coat contains pancreatin and bile extract, which are released in the duodenum and help the body absorb fats, proteins and carbohydrates.
Thus, the drug "Panzinorm", reviews of which are so good, has not only a substitute, but also a stimulating effect. The active components of bile and pancreas are included in all enzyme preparations. Such a course of therapy improves the functional state of the entire gastrointestinal tract and normalizes digestion as a whole.
It is worth noting that Panzinorm Forte 20000 will have a stronger effect (analogues to it are the medicine Macrozim Forte and Festal). These funds are characterized by a higher activity of the main components of the drug, which are released directly in the intestine.
Indications for use
The drug "Penzinorm", which analogs are easy to find in any pharmacy, can be used throughout the entire course of therapy or taken as an ambulance. Enzyme preparations can be prescribed in the following cases:
- As a replacement therapy with insufficient production of its own enzymes of the pancreas, intestines, liver, stomach and gall bladder. As well as with chronic diseases of these organs and in old age.
- As maintenance therapy for better digestion of food during normal gastrointestinal function and unhealthy diet. When consumed spicy, fatty foods and overeating.
- As a preparatory therapy before radiographic examinations of the abdominal cavity.
- The drug can be taken one-time as an ambulance for overeating or heaviness in the stomach after ingestion of heavy food.
Methods of taking the drug "Panzinorm"
How to drink tablets "Panzinorm" and "Panzinorm Forte"? The instructions for use contains the following recommendations regarding dosages and frequency of use.
Drink pills and capsules with a meal or a light snack, swallowing the medicine whole. Chewing is strictly forbidden, because the tool has special membranes that contribute to the release of active ingredients directly in the stomach and intestines.
Capsules "Panzinorm 10000" for adults appoint 2 pieces three times a day during the main meal and 1 capsule during a snack. The maximum amount is 15 pieces per day.
Children who have reached the age of three are advised to take the medicine in the same amount as adults.
The duration of therapy can vary from a single dose to several months, depending on the patient’s condition and the diagnosis.
Tablets "Panzinorm Forte" (reviews indicate a positive result of the reception) is prescribed in the same dosage, but remember that they are more active, so you should use their help only when you need to increase the number of enzymes.
Forms of release of the drug "Panzinorm" and analogues
The medicine "Panzinorm" is produced in tablets of 20,000 IU of Ph.Eur and capsules of 10,000 IU of Ph.Eur, hence the digital meaning in the name of the drug.
The capsules consist of a hard gelatin opaque body and a white lid with beige-brown pallets inside.
The tablets have a round biconvex shape and white or light gray color.
Capsules "Panzinorm 10000" can be replaced with tablets "Kreon 10000". The composition and action of these drugs are almost identical, and therefore interchangeable.
What to replace the "Panzinorm 20000"? Instructions for use for these tablets states that they contain 20,000 IU Ph.Eur, and therefore you need to find the appropriate dosage of lipase in the enzyme composition or drink two tablets of the drug Mezim, Pancreatin or Festal. A worthy analogue can also be considered a tool "Makrasim 10,000." Also, as a replacement, you can choose drugs marked "Forte", in which the main components have a higher activity.
Analog: Kreon capsulars
The drug "CREON" will make a worthy replacement for the drug "Panzinorm".Analogs of this class belong to complex enzyme preparations, which have a larger list of active components similar to the own secret of the stomach and intestines. Capsules are released with a dosage of 10,000, 25,000, 40,000 IU Ph.Eur.
The total single dose is established by the attending physician individually based on the general condition of the patient and the diagnosis. Experts recommend 1/2 or 1/3 of the total dosage to take before meals, and the balance - during (for better results). Capsules "CREON" can be used for the treatment of adults and children.
Analog: tablets "Pancreatin"
These pills are one of the cheapest substitutes for Panzinorm. Analogs of this kind are not always the best option, since a significant part of the substance is already dissolved in the stomach, and the concentration of the active ingredients in the Pancreatin tablets is already lower than in the Panzinorm capsules. In addition, the list of enzymes in the composition is much smaller, and therefore the Pancreatin tablets simply cannot compete with a richer and more effective composition.
Usually adults take "Pancreatin" 2-3 tablets, without chewing, during the meal. For children, the doctor sets the dosage individually.
Analog: Mezim Forte tablets
The drug "Mezim Forte", as well as tablets "Pancreatin", refers to inexpensive analogues. This is an excellent tool to relieve bloating, heaviness in the stomach with improper digestion and overeating. However, for the treatment of more serious diseases, the doctor is unlikely to prescribe this medicine. Its use is more suitable for a single use as an ambulance.
The following recommended doses are described in the instructions for this medicine:
- for adults 1-2 tablets before meals and 1-4 tablets during meals,
- children dosage is selected individually.
Reviews of enzyme preparations
Every adult was confronted with digestive problems, and every second child was diagnosed with various disorders of the gastrointestinal tract. Therefore, a huge number of people of different ages resorted to the use of enzyme preparations, such as tablets "Mezim" or "Panzinorm". Patient reviews confirm the positive effect of replacement or maintenance therapy.
Doctors also note an improvement in the work of the pancreas immediately after the start of the course of treatment, because enzyme medicines are designed not only to help the digestion of food, but also to restore the production of its own secret of the stomach and intestines.
Many parents give a positive assessment of the drugs "Panzinorm" and "Creon", appointed as maintenance therapy during the period of increasing acetone in children, when the digestive system works especially poorly.
Side effects and contraindications
Like all drugs, enzyme drugs have a number of contraindications and side effects. The drug is not prescribed in the following conditions:
- porcine protein intolerance,
- individual sensitivity to some components
- acute pancreatitis or exacerbation of chronic
- children under 15 with a diagnosis of
As a rule, the drugs "Panzinorm", "Panzinorm Forte", the analogues of these drugs do not cause any undesirable consequences, however, the cases of side effects were recorded:
- with intolerance to individual components, allergic reactions may occur,
- large doses of the drug can cause even greater gastrointestinal disorders.
With extreme caution should appoint the drug to patients with a diagnosis of cystic fibrosis.
Overdose and special instructions
As a rule, overdose with enzyme drugs does not cause systemic intoxication. Not an exception and the drug "Panzinorm 10,000." Analogues of this medicine can also cause only minor discomfort with the following symptoms:
- perianal irritation
- hyperuricuria and hyperuricemia.
With such manifestations should immediately seek medical help. Specialists in this case carry out symptomatic treatment, hydration and, naturally, cancel the medication.
Enzymes should be taken with caution when carrying and feeding a baby.
In order for the drug "Panzinorm" (including analogs) to retain its medicinal properties throughout the entire shelf life, it is necessary to ensure the necessary conditions for its storage: air temperature - not higher than 25 degrees, dry room and lack of sunlight.
"Pancreatin": a summary of the drug
This medicine has got its name by the name of the active active ingredient - Pancreatin, which is obtained by extracting beef or pork pancreas.
As a rule, the release form of "Pancreatin" - coated white or pink-colored tablets, but there are also tablets without a shell. The effectiveness of the latter is significantly lower, since part of the pancreatin is neutralized by caustic gastric juice.
Pancreatin is prescribed to patients for the treatment of the following diseases:
- Patient pancreatic insufficiency, including diseases such as chronic pancreatitis and cystic fibrosis,
- Inflammation of the tissues of the liver, gallbladder, stomach, including the chronic nature,
- Single intake for overeating, excess fat and heavy foods in the diet,
- A single reception in preparation for gastroscopic studies of internal organs,
- Recovery after resection, irradiation,
Pancreatin is famous for being very well tolerated by patients, rarely causing negative body reactions. However, there are a number of possible side effects:
- With long-term intake of large doses of the drug may increase the level of uric acid in the blood.
- Taking Pancreatin decreases the body's ability to absorb iron and folic acid.
It is because of the last point that Pancreatin is extremely undesirable for pregnant women, since anemia and folic acid deficiency can harm the formation of the fetus.
As a rule, when prescribing a long course of treatment with Pancreatin, the doctor prescribes iron supplements to the patient, and also regularly monitors this indicator in a clinical blood test.
Other contraindications to the use of the drug are:
- Exacerbation of chronic pancreatitis, acute form of the disease.
- Allergies to any component of the drug, including intolerance to pork or lactose.
- The patient is under three years old.
"Panzinorm": brief information about the drug
The active active ingredient in the composition of "Panzinorm" is the same. The release form of the drug - translucent capsules with granules of pancreatin inside. Due to the enteric shell of the capsule, the medicine safely passes the stomach and enters the small intestine, where it begins to act.
Take capsules with food, do not chew and wash down with plenty of water. In the event that the patient cannot swallow the capsule (for example, when it comes to small children), it is carefully opened and the contents are mixed with fruit puree.
The instructions for use indicate the following indications for the use of "Panzinorm":
- Insufficient production of pancreatic enzymes, including chronic pancreatitis and cystic fibrosis,
- Recovery after pancreatic and gastroectomy, as well as other surgical interventions in the organs of the gastrointestinal tract,
- Neoplasms in the pancreas,
- Obstruction of the bile ducts
Like other drugs of this group, Panzinorm has a number of contraindications:
- Hypersensitivity to one of the components of the drug, including pork intolerance,
- Exacerbation of chronic inflammatory processes in the pancreas,
- Pregnant women can use the drug with caution, after consulting with the leading pregnancy,
The list of side effects that may occur after taking Panzinorm is quite wide. As a rule, they occur after self-administration of inadequately large doses of the drug:
- There may be skin rashes, itching, redness,
- Increased tearing,
- Bronchial spasms, airway obstruction,
- Other allergic reactions
- Nausea, vomiting,
- Peranal irritation,
- Constipation or diarrhea,
As a rule, in order to cope with the side effects of taking Panzinorm, it is enough to stop taking the drug. However, it is best to seek medical advice in order to conduct therapy and select a drug equivalent.
The difference between "Pancreatin" and "Panzinorm"
After reviewing the composition of drugs, their indications for use and contraindications, a logical question arises: how do they differ? And is there any point in buying a more expensive Panzinorm if it is no different from Pancreatin?
So, let's try to formulate the main differences between these drugs:
Manufacturer and price
"Pancreatin" is produced by enterprises of the CIS, its cost is about 50 rubles for 60 tablets. Panzinorm manufactures a world-famous pharmaceutical company KRKA, and the cost is already about 200 rubles for 30 tablets. The price factor can play an important role, because often the course of treatment with enzyme preparations is stretched for a long time and taking “Pancreatin”, rather than an expensive foreign counterpart, will help you save a lot.
Here we can definitely say that “Panzinorm” is much better. It contains more active substances, in addition, it has anti-inflammatory and anti-edematous properties, which is important for inflammatory processes in the gastrointestinal tract.
In addition, information on the amount of active active substance contained in one tablet can always be found on the “Panzinorm” package. In the case of "Pancreatin", these data are not available, as a rule, the manufacturer indicates only the range of values. But in general, the number of pancreatin in one tablet "Panzinorm" will be much more than in the domestic counterpart.
The scope of these drugs as well, although it intersects, but not completely. Indications for use "Panzinorm" significantly wider, primarily due to its properties to fight inflammation and swelling.
In general, we can say that Panzinorm, as a more modern medicine, is superior to Pancreatin. Due to the release form and excellent composition, each Panzinorm capsule acts much more efficiently than Pancreatin tablets. However, one should not forget about the accessibility factor.
The cost of Pancreatin is significantly lower, which can play a decisive role when it comes to long-term replacement therapy for pancreatic insufficiency.
We must not forget that any of these drugs should not be taken without consulting a doctor. Of course, there will be no negative consequences from taking one pancreatin tablet during the New Year holidays. But if we are talking about long-term treatment, then you should take your health with the utmost seriousness.
Both drugs have a number of contraindications and possible side effects that may occur with uncontrolled intake. In addition, the entry of enzymes from outside in people who do not suffer from diseases of the pancreas, can lead to the fact that it does not produce its own enzymes.
That is why it is the attending physician who must answer the question of what is better to take, in what doses and for how long.